Internal Medicine Research – Open Journal (ISSN: 2771-800X)
Internal Medicine Research – Open Journal, is an International, online journal to expedite rapid publication and to introduce unique innovations and discoveries in basic and clinical sciences of Internal medicine. It was founded by a group of scientists for medical research and clinical scholarly doctors from around the world, who are devoted to the promotion and advancement of our understanding of the diseases and their treatments. The journal essences on advancing therapeutic sciences produced from basic sciences, clinical, and research group or general well being exploration to coordinate looks into in all parts of human well being. In this regard the journal publishes unique & inventive scientific articles, editorials, discussions, advancements, current innovations in internal medicine and other information relevant to internal medicine and related fields.
The scope of the journal includes clinical medicine, epidemiology, prevention, health care delivery, curriculum development, internal medicine, cardiology, clinical immunology, clinical pharmacology, endocrinology, gastroenterology, geriatrics, haematology, contagious diseases, oncology, nephrology, neurology, nuclear medicine, palliative medicine, respiratory medicine and rheumatology.
You are welcome to submit your work to submissions@researchopenworld.com
Open Access Policy: This journal is an open access journal which provides immediate, worldwide, boundary free access to the full content of every distributed article without charging readers or their institutions for access. Readers are given authorization to read, circulate, copy, print, download, search, or link to the full texts of all articles in IMROJ.
Editorial Board
Editors In Chief
Prof. Giuseppe Murdaca, Ph.D.
Expertise in Immunology,
Department of Internal Medicine,
University of Genova,
ITALY
Adel Ekladious
Senior consultant and Professor of Medicine
Bunbury Regional Hospital
University of Western Australia
Australia
Dr.Amr Edrees, M.D.
Specialization in Rheumatology,
Internal Medicine,University of Missouri,
Kansas City,
USA
Prof. Federico Cacciapuoti
Department of Internal Medicine,
Faculty of Medicine,
Second University of Naples,Naples,
ITALY
Dr.Francesco Bellanti
Hepatology,
Internal Medicine (General Medicine),
University of Foggia,Foggia,
ITALY
Dr.Burak Uz, MD
Gazi University Faculty of Medicine,
Department of Internal Medicine,
Division of Adult Hematology, Ankara,
Turkey
Dr.Gaurav K.Sharma, MD
The Department of Internal Medicine,
Mercy Hospital and Medical Center,
Chicago,
USA
Dr.Chaddha Ashish
Department of Internal Medicine,
University of Wisconsin Hospital and Clinics,Madison,
USA
Prof. Monica Lamberti
Second University of Naples,
Caserta,
Campania,
ITALY
Dr.Rahul Vasudev, Ph.D.
New York Medical college,
St Joseph’s Regional Medical Center,
New Jersey,
USA
Prof. Yoshitaka Fukuzawa
Professor and Director,
Preemptive and Integrative Medicine Center,
Aichi Medical University &
Aichi Medical Hospital,
Japan
Prof. Chung-Yi Chen
Dean and Professor,
School of Medical and Health Sciences,
Fooyin University, Taiwan,
CHINA
Dr.Fadi Haddad
Department of Internal Medicine,
Staten Island University Hospital/Northwell Health,Staten Island,NY,
USA
Prof. Massimo Ciccozzi
International Education, Didactics, Adult Education,
Department of Infectious Diseases,
Italian National Institute of Health, Rome,
ITALY
Dr.Luigi Pagliaro
Professor Emeritus of Internal Medicine,
University of Palermo,
Palermo,
ITALY
Dr.Mahir Cengiz ,MD
Internal Medicine
(General Medicine),
University of Istanbul,Istanbul,
Turkey
Dr.Shadi Hamdeh
Creighton University School of Medicine,
Department of Internal Medicine,
Omaha, NE,
USA
Dr.Sumru Savas
Ege University,
Department of Internal Medicine,
Section of Geriatrics,Izmir,
Turkey
Dr.Katherine S Blondon, Ph.D.
Division of General Internal Medicine,
Geneva University Hospitals,
Geneva,
Switzerland
Dr.Wei-Gang Hu
Bio-Threat Defence Section,
Defence Research & Development Canada,
Suffield Research Centre,
Canada
Dr.Theodosios Filippatos ,MD,PHD
Department of Internal Medicine,
School of Medicine,
University of Loannina,Loannina,
Greece
Dr.Moses Elisaf
Professor of Medicine,
Director of the Second Department of Internal Medicine,University of Ioannina,
Greece
Dr.Nilay Patel
Internal Medicine Department,
Saint Peter’s University Hospital,
New Brunswick,NJ,
USA
Dr.Antonio Simone Laganà, M.D.
Unit of Gynecology and Obstetrics,
Department of Human Pathology in Adulthood and Childhood “G. Barresi”,University of Messina,
ITALY
Dr.Leonardo Roever
Department of Clinical Research,
Federal University of Uberlandia(UFU),
Uberlandia,
Brazil
Prof. Essam Ahmed Al-Moraissi
Department of Oral and Maxillofacial Surgery,
Faculty of Dentistry,
Thamar University,
Republic of Yemen
Dr.ITIR Yegenaga
Department of Internal Medicine,
Kocaeli University Medical School,
Kocaeli,
Turkey
Published Articles
Future in Physiological Pacing? State of the Art
Daniel Felipe Ortega
Perspective – Internal Med Res Open J
Metformin Use and Mortality among Prostate Cancer Patients
Huan-ju Shih, Hua Min, Janusz Wojusaik and Panagiota Kitsantas
Research Article – Internal Med Res Open J
Inguinal Hernias Repair by Laparascopy (TEP)
Olga Caridad León González, Pedro Rolando López Rodríguez, Lais Angélica Ceruto Ortiz, Jorge Agustín Satorre Rocha, Eduardo García Castillo, et al.
Research Article – Internal Med Res Open J
Alcohol and Health: Social Evolution, Production and Control
Paul Durrington and Handrean Soran
Research Article – Internal Med Res Open J
Revision of Sex Hormone Replacement Therapy for CKD Pediatric Cases
Davoud Amirkashani MD and Sedigheh Madani MD
Letter to the Editor – Internal Med Res Open J
From Evolutionary Medicine to Precision Medicine in the Hypertension Treatment in Africa
Ângela Inácio, Laura Aguiar and Manuel Bicho
Review Article – Internal Med Res Open J
Mark B. Zimering
Research Article – Internal Med Res Open J
Rita Conigliaro
Review Article – Internal Med Res Open J
Effects of Radiation on Mitochondrial Defective Lymphoblastoid Cells
Jessica Chen, Deepa Sridharan, Chad Cross and Janice Pluth
Review Article – Internal Med Res Open J
How are Vitamin B12 and S-Adenosylmethionine Related?
Perry Allen Frey
Review Article – Internal Med Res Open J
Ovarian Cystadenocarcinoma with an Osteosarcoma Component
Pr S Sakhri esp Boulhart
Case Report – Internal Med Res Open J
Sandro Norelli
Research Article – Internal Med Res Open J
Peter-Hansen Volkmann
Commentary – Internal Med Res Open J
Highly Anomalous Electroencephalographic Synchronized Pattern during Wakefulness
Jesús Pastor and Lorena Vega-Zelaya
Case Report – Internal Med Res Open J
Karthikeyan T
Research Article – Internal Med Res Open J
Case Report of Successful Lung Therapy in COVID-19
Schneider N
Letter to Editor – Internal Med Res Open J
The Challenge of Integrated Care
Stephen R Leeder and Christopher Kazuma Thien-Tam Le
Short Commentary – Internal Med Res Open J
Luosheng Huang
Research article – Internal Med Res Open J
Mechanisms of Anti-Melanogenic and Proliferative Effects of Colla Corii Asini (E’jiao)
Chien Wei Hou
Research article – Internal Med Res Open J
Johnson-Ajinwo OR and Nyodee Dummene Godwin
Research article – Internal Med Res Open J
The Status Quo in Health Risk Assessment of Chronic Diseases and Challenges Faced by China
Yalan Zhang, Li Sun and Zongtao Chen
Review article – Internal Med Res Open J
SK Singh, Jitendra Chouhan and Rujul Jain
Research Article – Internal Med Res Open J
The Impact of Culture and Beliefs in Cancer Care: Turkish Experience
Sedat Ozkan
Research Article – Internal Med Res Open J
The Organization of the Dental Service in the Voronezh Region
Antonenkov Yu E
Research Article – Internal Med Res Open J
Double-Blind Testing of the Lifewave X39 Patch to Determine GHK-Cu Production Levels
Caitlin A Connor, Melinda H Connor, David Yue, Jens Eickhoff, Susan Wagner and Amy Chang
Research Article – Internal Med Res Open J
Thibaut Sanchez, Frédéric Lagarrigue and Véronique Le Cabec
Short Commentary – Internal Med Res Open J
A Safety Signal’s Significance with the COVID-19 Coronavirus
Thomas W Miller
Review Article – Internal Med Res Open J
Zhongping Cao
Review Article – Internal Med Res Open J
Metabolomic Analysis Unfolds Connection of Obesity and Endometrial Cancer
Valentina L. Kouznetsova, Kevin Q. Wang, Benjamin K. Pham and Igor F. Tsigelny
Research Article – Internal Med Res Open J
Мaria Studneva, Anton Yuryev, Veronica Medvedeva, Hiroyuki Abe, Elena Antonova, Vassiliy Tsytsarev, Trevor Marshall, Andrew D Miller and Sergey Suchkov
Review Article – Internal Med Res Open J
Gerald C Hsu
Research Article – Internal Med Res Open J
Evans Paul Kwame Ameade, Isaac Bonney and Evans Twumasi Boateng
Research Article – Internal Med Res Open J
Narayan Bahadur Basnet
Short Communication – Internal Med Res Open
Gerald C Hsu
Research Article – Internal Med Res Open
Personalised Approaches in Treating Early-Stage Hodgkin Lymphoma
Tim Illidge and Elizabeth H Phillips
Editorial Commentary – Internal Med Res Open J
In Vitro and Intracellular Activities of Omadacycline against Staphylococcus aureus Isolates
Jacques Dubois, Maïtée Dubois and Jean-Francois Martel
Research Article – Internal Med Res Open J
Obesity and Inflammatory Profile: Is Physical Exercise Able to Reverse This Process? A Mini Review
Tito Cardoso de Almeida Mafra, Christiane Salum Machado Simões, Marcus Vinicius Gomes Cezar Vieira, Lı́via Ribeiro Borges Lazzarotto, et al.
Review Article – Internal Med Res Open J
CoVid-19 its Impact on Healthcare Workers and the Need for Occupational Healthcare Provision
Yuke Tien Fong, Jonathan Lam WY, Chua Yeow Leng and Tay Boon Keng
Review Article – Internal Med Res Open J
Gerald C Hsu
Review Article – Internal Med Res Open J
Gerald C Hsu
Review Article – Internal Med Res Open J
An Uncommon Cause of Bilateral Pulmonary Nodules in a Long-Term Smoker
Alameeri Amel, Lane Stephen, Mohammed Nur Mutaz, Loftus Barbara and Hogan Brenden
Case Report – Internal Med Res Open J
SARS-Cov2: A Review of this Novel Coronavirus
Dominic Worku and Elliott Worku
Research Article – Internal Med Res Open J
Malignant Urinary bladder paraganglioma in 12 year old boy
Kushagra Gaurav, Priyank Yadav, Aditi Chopra, Saroj Kanta Mishra and Uday Pratap Singh
Case Report – Internal Med Res Open J
Relationship between polycystic ovarian syndrome (PCOS) and fatty liver disease
Sikandar Hayat Khan, Sohail Aslam, Rahat Shahid, Robina Manzoor, Roomana Anwar and Tariq Chaudhry
Research Article – Internal Med Res Open J
Management of Diabetes Patients across the Peri- Operative Pathway: A Systematic Review
Jennifer Wallace, Shahwar Jiwani, Philemon Gyasi-Antwi, Andrew Meal, Gary G. Adams
Research Article – Internal Med Res Open J
Blood Transfusion Guided by Physiological Markers
Mario A Rodríguez Domínguez, Ana Maria Espinosa-Galindo, Luis Javier Marfil-Rivera and Dionisio Palacios-Ríos
Research Article – Internal Med Res Open J
Urinary Prothrombin Fragment 1 + 2 as an Endogenous Marker of Venous Thromboembolism
Fredrik Wexels, Walter Jeske, Ola E. Dahl and Jawed Fareed
Research Article – Internal Med Res Open J
First Case Report of Pancreatitis in Lyme disease
A Baisse, S Parreau, A Abdeh and N Pichon
Case Report – Internal Med Res Open J
Thoughts at a White Coat Ceremony
Robert T. Means, Jr.
Perspective Article – Internal Med Res Open J
Luana Ramalho Jacob, Ana Paula Correa, Fernanda do Nascimento Maia, Dafne Dain Gandelman Horovitz, Carla Trevisan Martins Ribeiro
Research Article – Internal Med Res Open J
The Impact of Accountable Care Units on Patient Outcomes
David H. Howard, Susan E. Shapiro, David J. Murphy, Elizabeth C. Overton, Liam Chadwick and Jason M. Stein
Research Article – Internal Med Res Open J
Margaux Geier, MD
Research Article – Internal Med Res Open J
Expectations and Attitudes Regarding Chronic Pain Control: An Exploration Using Mind Genomics
Gillie Gabay, Attila Gere, Glenn Zemel, Danny Moskowitz, Ran Shifron and Howard Moskowitz
Research Article – Internal Med Res Open J
Blood Pressure in Healthy Youngsters is modified by Vitamin-D Supplementation
Rune Tønnesen, Kristian Buch, Peter Hambak Hovind, Lars Thorbjørn Jensen and Peter Schwarz
Research Article – Internal Med Res Open J
Richard Conway, Declan Byrne, Deirdre O’Riordan and Bernard Silke
Research Article – Internal Med Res Open J
Oral Glucose Tolerance Test with Cooked Rhizomes of Zingiber Officinale (Ginger)
Mohammed Abdul Mannan, Khoshnur Jannat and Mohammed Rahmatullah
Research Article – Internal Med Res Open J
Diagnostic and Prognostic Value of Serum Cyfra 21–1 Levels in Patients with Pancreatic Cancer
Jung Hoon Kim, Young Chul Yoon, Joon Cheol Song, Jeong Won Jang and In Sook Woo
Research Article – Internal Med Res Open J
Burroughs Wellcome: The Seminal Link between Academia and the Pharmaceutical Industry
Ronald P. Rubin, PhD
Review Article – Internal Med Res Open J
The Impact of Type 2 Diabetes on Periodontal Health in Elderly Subjects: Princeps Study
Abrar-Ahmad Zulfiqar, M.D, MSc, Jean Doucet, M.D, Ph.D and Hervé Moizan, Ph.D
Letter to the Editor – Internal Med Res Open J
David J Chinn, Alison Lowrie, Tahir A Mahmood, Helen M Colhoun and Ian W Campbell
Research Article – Internal Med Res Open J
Global Healthcare Workers Migration: A Human Resource Management Concern
James Ducey and Satesh Bidaisee
Review Article – Internal Med Res Open J
Cross-sectional Study Investigating Texting and Driving in Grenada, West Indies
James A Ducey, Ryan Malave, Iman Zahedi, Emmanual Keku and Satesh Bidaisee
Review Article – Internal Med Res Open J
Low levels of HDL-cholesterol and endothelial dysfunction: a systematic review and meta-analysis
Leonardo Roever, MHS, Elmiro Santos Resende, PhD, Angélica Lemos Debs Diniz, PhD, Nilson Penha-Silva, PhD, João Lucas O’Connell, PhD, Fernanda Rodrigues de Souza, PhD, Poliana Rodrigues Alves Duarte, PhD, Paulo Fernando Silva Gomes, MD, Américo José Caixeta Neto, Lívia Maria Ambrósio da Silva, Rosangela de Oliveira Felice, Hugo Ribeiro Zanetti, MSc, Anaisa Silva Roerver-Borges, MD, Fernando César Veloso, MHS, Thiago Montes Fidale, PhD, Antonio Casella-Filho, PhD, Paulo Magno Martins Dourado, PhD, Antonio Carlos Palandri Chagas, MD, PhD, Sadeq Ali-Hasan-Al-Saegh, MD, Paulo Eduardo Ocke Reis, PhD, Rogério de MeloCosta Pinto, PhD, Gustavo B. F. Oliveira, PhD, Álvaro Avezum, PhD, Mansueto Neto, PhD, André Durães, PhD, Rose Mary Ferreira Lisboa da Silva, PhD, Antonio José Grande, PhD, CeliseDenardi, MD, Renato Delascio Lopes MD, PhD, NiteshNerlekar, MD, Shahab Alizadeh, MSc, Adrian V. Hernandez, MD, PhD, Maria Inês da Rosa, MD, PhD, Gary Tse, MD, PhD, Tong Liu, MD, PhD, Giuseppe Biondi-Zoccai, MD, MStat
Review Article – Internal Med Res Open J
Simon A Costello, and Margaret Staples
Original Article – Internal Med Res Open J
Xue Liang, Han Wang, Xiao Mao, Zhiqiong Wang, Wei Huang
Short Communications – Internal Med Res Open J
A Possible Role for Midkine in the Pathogenesis of Behçet’s Syndrome
A. Şükrü Aynacıoğlu, Ayhan Bilir, and M. Yakup Tuna
Review Article – Internal Med Res Open J
Gerhard Domagk (1895-1964) and the Origin of Anti- Bacterial Therapy
Ronald P. Rubin
Review Article – Internal Med Res Open J
Retrospective Study of 133 Canadian Hidradenitis Suppurativa Patients and Literature Review
Erika L. Crowley, Claudia J. Posso-De Los Rios, Melinda J. Gooderham
Review Article – Internal Med Res Open J
Caitlin McCarthy and M. Thomas Bateman
Research Article – Internal Med Res Open J
Graham Wilfred Ewing
Review Article – Internal Med Res Open J
Gary Lynch, Paul Kennedy, Stephen Bergin, Siobhan Glavey, Philip W Murphy, John Quinn, and Philip T Murphy
Short Report – Internal Med Res Open J
Serum 25-hydroxyvitamin D and Osteocalcin Levels and Insulin Sensitivity in Young Women
Do Kyeong Song, Hyejin Lee and Yeon-Ah Sung
Research Article – Internal Med Res Open J
Plasma Visfatin is reduced in Subjects with the Metabolic Syndrome and Pre-Diabetes
Brema I, Thabit H, Shah S, Burns N, Gasparro D, Crowley V, Storka A, Wolzt M and Nolan JJ
Research Article – Internal Med Res Open J
Relationship between Breast, Formula and Combination Feeding on Childhood in Italy
A. Arrichiello, F. Frezza, G. Auriemma, R. Palomba, and F. Sarubbi
Research Article – Internal Med Res Open J
Pallavi Panth, Alexis Neal, Nancy DiMarco, and Larry Petterborg
Research Article – Internal Med Res Open J
Nhiem Viet Luong, Mamadou Diallo, Laura Gannon, Martin Luta and Awele Maduka-Ezeh
Research Article – Internal Med Res Open J
Surrogate Markers of Liver Fibrosis in Primary Sclerosing Cholangitis (PSC)
Monika Szydlowska-Jakimiuk, Joanna Raszeja-Wyszomirska
Research Articles – Internal Med Res Open J
Kadir Demir, Cetin Karaca, Emel Ahishali, Metban Mastanzade, Selda Celik, Nurdan Gul, Fulya Turker, Filiz Akyuz, Fatih Besisik, and Kubilay Karsidag
Research Article – Internal Med Res Open J
Miriam Kidron, Yael Greenberg-Shushlav, Roy Eldor and Ehud Arbit
Short Communication – Internal Med Res Open J
Gregory Oxenkrug, Marieke van der Hart, Julien Roeser, and Paul Summergrad
Research Article – Internal Med Res Open J
Identification Potency of Clinical Isolates in Aspergillus Species Using MALDI-TOF MS
Norihito Tarumoto, Jun Sakai, Keisuke Sujino, Takuya Maeda, Mayu Ohta, Toshiyuki Yamaguchi, Takashi Murakami, Hideaki Ohno and Shigefumi Maesaki
Research Article – Internal Med Res Open J
Sklar M, Coleman M, Campbell S, Yeracaris P, Hurwitz D, Hewitt S, Fortin EW and Goldman RE
Research Article – Internal Med Res Open J
WHR is a Better Predictor of Type 2 DM Among Urban Adults in Jos, North Central, Nigeria
Aniekwensi Ezechukwu C and Fabian H Puepet
Research Article – Internal Med Res Open J
Hormonal Aspects of Post-Traumatic Stress Disorder
Lindsey M VanDyke, L Elisabeth Burton, Ajna Hamidovic, Mark R Burge
Research Article – Internal Med Res Open J
Ulrika Morris, Mwinyi Khamis, Berit Aydin-Schmidt, Ali K Abass, Mwinyi I Msellem, et al.
Research Article – Internal Med Res Open J
Is Intravenous Iron Treatment a Risk for Infection?
Emilio Fábrega, María José García, Carmen Alonso, Manuel Fernandez-Miera, et al.
Research Article – Internal Med Res Open J
Humanized Monoclonal Antibodies in Pulmonology: An Integrated Review
Arzu DidemYalcin, Kevser Onbasi, RusenUzun, Felix Herth, Philipp Albert Schnabel
Review Article – Internal Med Res Open J
The Usefulness of the Rate Pressure Product (RPP) for Cardiac Rehabilitation Exercise Prescription
Sherldine Tomlinson
Review Article – Internal Med Res Open J
Basic Food Safety Practise of Open-Air-Market Vending In The Eastern Highlands Of Papua New Guinea
Johnson Makaen, Tobias Maure and Sauli Bebes
Research Article – Internal Med Res Open J
Obesity and Kidney Disease: Hidden Consequences of the Epidemic
Csaba P. Kovesdy, Susan Furth and Carmine Zoccali
Research Article – Internal Med Res Open J
H Pylori Infection as Risk Factor for GIT Bleeding in Haemophilic Patients
Noha M El Husseiny, Louis Essac and Mona Al Kassas
Research Article – Internal Med Res Open J
Mahmoud Abdelaal, Carel W le Roux and Neil G Docherty
Research Article – Internal Med Res Open J
Restraint Use in the Management of the Elderly with Dementia in Hospital
Lim SC, Poon WH
Review Article – Internal Med Res Open J
Avinash Aujayeb, Joseph Mackenzie
Case Report – Internal Med Res Open J
Evidence-Based Medicine (EBM) and Clinical Practice
Luigi Pagliaro
Editorial – Internal Med Res Open J
ITIR Yegenaga
Editorial – Internal Med Res Open J
Developing Nutrition Awareness in First Year Medical Students
Bruckner Geza, Elder William and Sehnert Scott
Research Article – Internal Med Res Open J
Takeda-Raguin C, Vogel T and Lang PO
Research Article – Internal Med Res Open J
Novel Agents for the Treatment of Hereditary Hemorrhagic Telengiectasia: Are They Effective Enough?
Burak Uz
Editorial – Internal Med Res Open J
Ileum Ulcer Bleeding By Cytomegalovirus Infection In A Colon Cancer Patient
Hui-Chun Chao, Khee-Siang Chan and Wen-Liang Yu
Case Report – Internal Med Res Open J
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